Publications
Selected recent pulications:
Chen C, Merrill RA, Jong CJ, Strack S. Driving Mitochondrial Fission Improves Cognitive, but not Motor Deficits in a Mouse Model of Ataxia of Charlevoix-Saguenay. Cerebellum. 2024 May 13. doi: 10.1007/s12311-024-01701-1. Online ahead of print. PMID: 38735882
Hardy JC, Pool EH, Bruystens JGH, Zhou X, Li Q, Zhou DR, Palay M, Tan G, Chen L, Choi JLC, Lee HN, Strack S, Wang D, Taylor SS, Mehta S, Zhang J. Molecular determinants and signaling effects of PKA RIα phase separation. Mol Cell. 2024 Apr 18;84(8):1570-1584.e7. doi: 10.1016/j.molcel.2024.03.002. Epub 2024 Mar 26. PMID: 38537638
Protein Kinase A in neurological disorders. Glebov-McCloud AGP, Saide WS, Gaine ME, Strack S.
J Neurodev Disord. 2024 Mar 13;16(1):9. doi: 10.1186/s11689-024-09525-0. PMID: 38481146 Free PMC article. Review.
Wu CG, Balakrishnan VK, Merrill RA, Parihar PS, Konovolov K, Chen YC, Xu Z, Wei H, Sundaresan R, Cui Q, Wadzinski BE, Swingle MR, Musiyenko A, Chung WK, Honkanen RE, Suzuki A, Huang X, Strack S*, Xing Y*.
B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e2310727120. doi: 10.1073/pnas.2310727120. Epub 2023 Dec 27. PMID: 38150499 Free PMC article. *co-correspondence
Guo DF, Merrill RA, Qian L, Hsu Y, Zhang Q, Lin Z, Thedens DR, Usachev YM, Grumbach I, Sheffield VC, Strack S, Rahmouni K. The BBSome regulates mitochondria dynamics and function. Mol Metab. 2023 Jan;67:101654. doi: 10.1016/j.molmet.2022.101654. Epub 2022 Dec 10. PMID: 36513220 Free PMC article.
Sandal P, Jong CJ, Merrill RA, Song J, Strack S. Protein phosphatase 2A - structure, function and role in neurodevelopmental disorders. J Cell Sci. 2021 Jul 1;134(13):jcs248187. doi: 10.1242/jcs.248187. Epub 2021 Jul 6. PMID: 34228795 Free PMC article. Review.
Song J, Merrill RA, Usachev AY, Strack S. The X-linked intellectual disability gene product and E3 ubiquitin ligase KLHL15 degrades doublecortin proteins to constrain neuronal dendritogenesis. J Biol Chem. 2021 Jan-Jun;296:100082. doi: 10.1074/jbc.RA120.016210. Epub 2020 Nov 21. PMID: 33199366 Free PMC article.
Jong CJ, Merrill RA, Wilkerson EM, Herring LE, Graves LM, Strack S. Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B'δ holoenzyme. J Biol Chem. 2020 Apr 24;295(17):5654-5668. doi: 10.1074/jbc.RA119.011270. Epub 2020 Mar 10. PMID: 32156701 Free PMC article.
Flippo KH, Lin Z, Dickey AS, Zhou X, Dhanesha NA, Walters GC, Liu Y, Merrill RA, Meller R, Simon RP, Chauhan AK, Usachev YM, Strack S. Deletion of a Neuronal Drp1 Activator Protects against Cerebral Ischemia. J Neurosci. 2020 Apr 8;40(15):3119-3129. doi: 10.1523/JNEUROSCI.1926-19.2020. Epub 2020 Mar 6. PMID: 32144179
Liu Y, Merrill RA, Strack S. A-Kinase Anchoring Protein 1: Emerging Roles in Regulating Mitochondrial Form and Function in Health and Disease. Cells. 2020 Jan 26;9(2):298. doi: 10.3390/cells9020298. PMID: 31991888 Free PMC article. Review.